Adenovirus-Mediated Combined Cytotoxic and Immune-Stimulatory Gene Therapy Using Dual-Vector Ad-hCMV-TK and Ad-hCMV-Flt3L: Translational Explorations from Rodents to Glioma Patients

The authors provide a thorough overview of immune stimulatory gene therapy highlighting recent advancements, potential drawbacks, future directions, and recommendations for future implementation of clinical trials.