Scientists showed that Tet2 deficiency significantly facilitated leukemogenesis in various AML models through promoting homing of leukemia stem cells into bone marrow niche to increase their self-renewal/proliferation.
[Cell Stem Cell]
Home Newsletters Hematopoiesis News TET2-Mediated mRNA Demethylation Regulates Leukemia Stem Cell Homing and Self-Renewal
