Muscle Cell News
Muscle Cell News is an online resource dedicated to the latest research into smooth, skeletal, and cardiac muscle cells.
Nanoparticle-Driven Skeletal Muscle Repair and Regeneration through Macrophage-Muscle Stem Cell Interaction
[Small] The authors synthesized lipoic acid-modified gold nanoparticles of varying sizes to evaluate their biocompatibility and immunomodulatory effects.
ZIP13 Marks Muscle Satellite Cells and Contributes to Their Quiescent and Active Phase Balance
[Scientific Reports] investigated Zip13-knockout (KO) mice and found a reduction in muscle satellite cells of Zip13-KO mice, in which the quiescent and activated phase balances were disrupted.
PLK1 Downregulation Attenuates ET-1-Induced Cardiomyocyte Hypertrophy by Suppressing the ERK1/2 Pathway
[Journal of Cardiovascular Translational Research] The authors found polo-like kinase 1 was crucial in regulating endothelin-1-induced cardiomyocyte hypertrophy.
Nrf3-Mediated Mitochondrial Superoxide Promotes Cardiomyocyte Apoptosis and Impairs Cardiac Functions by Suppressing Pitx2
[Circulation] Global and cardiomyocyte-specific Nrf3 knockout mice were subjected to myocardial infarction or ischemia/reperfusion injury, followed by functional and histopathological analysis.
A Novel Hidden Protein p-414aa Encoded by circSETD2(14,15) Inhibits Vascular Remodeling
[Circulation] Cell proliferation assays were performed to investigate the effects of circSETD2(14,15) on vascular smooth muscle cell proliferation.
Cellular Senescence in the Regenerative Niche Hampers Skeletal Muscle Repair
[Aging and Disease] Investigators summarize emerging findings and technologies in muscle regeneration, analyzing therapeutic potential and limitations of current approaches for age-related conditions to support research advancement.
Queen’s Researchers Secure $7.5M in Federal Health Funding
[Queen’s University] The Canadian Institutes of Health Research (CIHR) have announced the recipients of their latest Project Grant fund. Researchers at Queen’s have secured $7.5 million for projects that demonstrate exciting potential to advance health research and impact health outcomes.
FoxO3 Controls Cardiomyocyte Proliferation and Heart Regeneration by Regulating Sfrp2 Expression in Postnatal Mice
[Nature Communications] Researchers showed that forkhead box O3 (FoxO3) deficiency promoted cardiomyocyte proliferation in postnatal mice and improved cardiac function in homeostatic adult mice.
Rhein Alleviates Diabetic Cardiomyopathy by Inhibiting Mitochondrial Dynamics Disorder, Apoptosis, and Hypertrophy in Cardiomyocytes
[Cellular Signalling] Streptozotocin-induced diabetic cardiomyopathy mice, high-glucose-treated neonatal rat cardiomyocytes, and H9c2 cells with ClpP knockdown were used for the study.
SH3KBP1 Promotes Skeletal Myofiber Formation and Functionality through ER/SR Architecture Integrity
[EMBO Reports] To find factors associated with muscle integrity, investigators perform an siRNA screen and identify SH3KBP1 as a new factor controlling myoblast fusion, myonuclear positioning, and myotube elongation.
Mitochondrial Fatty Acid Oxidation Regulates Adult Muscle Stem Cell Function through Modulating Metabolic Flux and Protein Acetylation
[EMBO Reports] Scientists uncovered a role of mitochondrial fatty acid oxidation in satellite cell integrity and function.
Muscle-Specific Keap1 Deletion Enhances Force Production but Does Not Prevent Inactivity-Induced Muscle Atrophy in Mice
[FASEB Journal] Investigators determined whether muscle-specific Keap1 deletion was sufficient to prevent muscle atrophy and weakness in mice following seven days of hindlimb unloading.
Every day, our editorial team sifts through the most recent scientific literature to help keep researchers and medical professionals current. Muscle Cell News covers the three types of muscle cells: cardiac, skeletal, and smooth muscle. We cover a broad range of topics, including cell culturing, muscle regeneration, and musculoskeletal disorders.
