Endothelial Cell News
Endothelial Cell News is an online resource dedicated to the latest research studying the endothelium, blood vessels, and angiogenesis.
Engineering VEGF-Like Peptide QKCMP Promotes Rapid Endothelialization of Blood Vessels
[Journal of Applied Biomaterials & Functional Materials] Zebrafish were treated with different concentrations of QKCMP, and it was found that QKCMP significantly promoted the growth of blood vessels.
Impaired Endothelial Function Contributes to Cardiac Dysfunction – Role of Mitochondrial Dynamics
[American Journal of Physiology-Heart and Circulatory Physiology] Mitochondrial dynamics is an important autoregulatory mechanism that contributes to mitochondrial and endothelial homeostasis and plays a role in formation of reactive oxygen species.
Tumor-Derived Extracellular Vesicles Disrupt the Blood–Brain Barrier Endothelium following High-Frequency Irreversible Electroporation
[Scientific Reports] The authors showed that small tumor-derived extracellular vesicle increase permeability of the blood–brain barrier endothelium after high-frequency irreversible electroporation ablation in vitro.
EphrinB2-Mediated CDK5/ISL1 Pathway Enhances Cardiac Lymphangiogenesis and Alleviates Ischemic Injury by Resolving Post-MI Inflammation
[Signal Transduction and Targeted Therapy] Scientists revealed that erythropoietin-producing hepatoma interactor B2 (EphrinB2) prevented ischemic heart post-myocardial infarction from remodeling and dysfunction by activating the cardiac lymphangiogenesis signaling pathway.
Tumor-Derived EBV-miR-BART2-5p Promotes Nasopharyngeal Carcinoma Metastasis by Inducing Pre-Metastatic Endothelial Cell Pyroptosis
[Molecular Cancer Research] The authors showed that the expression of pyroptosis-associated proteins was greater in the endothelial cells of metastatic nasopharyngeal carcinoma tissues than in those of nontumor tissues.
Endothelial Progenitor Cell-Derived Conditioned Medium Mitigates Chronic Cerebral Ischemic Injury Through Macrophage Migration Inhibitory Factor-Activated AKT Pathway
[Stem Cell Research & Therapy] Endothelial progenitor cell-derived conditioned medium was analyzed by cytokine array to identify key factors involved in angiogenesis and cellular senescence.
N-Acetylneuraminic Acid Triggers Endothelial Pyroptosis and Promotes Atherosclerosis Progression via GLS2-Mediated Glutaminolysis Pathway
[Cell Death Discovery] Researchers constructed GLS2−/−ApoE−/− mice by using HBLV-GLS2 shRNA injection. Immunofluorescence, western blotting, transmission electron microscopy were applied to detect profiles of endothelial injury and atherosclerosis progression.
Catalpol Regulates Apoptosis and Proliferation of Endothelial Cell via Activating HIF-1α/VEGF Signaling Pathway
[Scientific Reports] Scientists investigated whether Catalpol regulated apoptosis and proliferation following vascular injury induced by burns using an in vitro model of oxygen-glucose deprivation with a HUVEC line.
Extracellular Vesicles Derived from Endothelial Progenitor Cells Modified by Houshiheisan Promote Angiogenesis and Attenuate Cerebral Ischemic Injury via miR-126/PIK3R2
[Scientific Reports] Researchers investigated the impact of Houshiheisan-modified xtracellular vesicles-derived extracellular vesicles on angiogenesis using rats with permanent middle cerebral artery occlusion and brain microvascular endothelial cells subjected to oxygen-glucose deprivation.
SIRT3 Deficiency Promotes Lung Endothelial Pyroptosis through Impairing Mitophagy to Activate NLRP3 Inflammasome during Sepsis-Induced Acute Lung Injury
[Molecular and Cellular Biology] Scientists investigated the effects of sirtuin 3 deficiency on impaired mitophagy to promote lung endothelial cell pyroptosis during sepsis-induced acute lung injury.
Sandoz Receives European Commission Approval for Afqlir® (Aflibercept), Further Strengthening Leading Biosimilar Portfolio
[Sandoz] Sandoz announced that the European Commission has granted marketing authorization for Afqlir® 2 mg vial kit and pre-filled syringe for intravitreal injection. Afqlir® is indicated to treat various retinal diseases, including neovascular age-related macular degeneration.
Endothelial Heterogeneity in Bone Marrow: Insights Across Development, Adult Life, and Leukemia
[Leukemia] The authors highlight key milestones and recent advances in understanding vascular heterogeneity within bone marrow microenvironment during development, adulthood, and aging.
Specific research topics covered in Endothelial Cell News include the roles of endothelial cells in the regulation of physiological processes, as well as their implications in tumor progression, cardiovascular disease, endometriosis, wound healing, tissue regeneration and other diseases and disorders. We also provide updates on the latest job postings and upcoming events, helping connect everyone within the endothelial cell research field.
