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Endothelial Cell News
Endothelial Cell News is an online resource dedicated to the latest research studying the endothelium, blood vessels, and angiogenesis.
Multi-Omics Analysis of Human Tendon Adhesion Reveals That ACKR1-Regulated Macrophage Migration Is Involved in Regeneration
[Bone Research] Scientists found that SPP1+ macrophages, RGCC+ endothelial cells, ACKR1+ endothelial cells and ADAM12+ fibroblasts participated in tendon adhesion formation.
Aging-Regulated PNUTS Maintains Endothelial Barrier Function via SEMA3B Suppression
[Communications Biology] Investigators determined the role of Phosphatase 1 Nuclear Targeting Subunit (PNUTS) in endothelial cell aging. They confirmed that PNUTS was repressed in senescent endothelial cells.
Translational Research of the Acute Effects of Negative Emotions on Vascular Endothelial Health: Findings from a Randomized Controlled Study
[Journal Of The American Heart Association] The authors examined the acute effects of provoked anger, and secondarily, anxiety and sadness on endothelial cell health.
New $2 Million Research Initiative Will Study Heart and Brain Health in People With Autism
[American Heart Association] According to the US Centers for Disease Control and Prevention, 1 in 36 children and 1 in 45 adults in the US have autism, a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.
Betaglycan Sustains HGF/Met Signaling in Lung Cancer and Endothelial Cells Promoting Cell Migration and Tumor Growth
[Heliyon] Scientists found that HGF/Met promoted lung cancer and endothelial cells migration via PI3K and mTOR. This effect was enhanced by recombinant soluble betaglycan via a mechanism attributable to its glycosaminoglycan chains, as a mutant without them did not modulate HGF effects.
Hypoxia Modulates P-Glycoprotein (P-GP) and Breast Cancer Resistance Protein (BCRP) Drug Transporters in Brain Endothelial Cells of the Developing Human Blood-Brain Barrier
[Heliyon] The authors investigated how hypoxia impacts multidrug resistance transporters in human fetal brain endothelial cells derived from early and mid-stages of pregnancy.
Metabolic Reprogramming and Interventions in Angiogenesis
[Journal Of Advanced Research] The authors discuss the metabolic regulation of angiogenesis by endothelial cell (EC) metabolites and metabolic enzymes, as well as prospect the possible therapeutic opportunities and strategies targeting EC metabolism.
Tissue-Engineered Microvessels: A Review of Current Engineering Strategies and Applications
[Advanced Healthcare Materials] Scientists summarize recent progress in engineering approaches, key components, and culture platforms for tissue-engineered human microvessel models.
MCG Scientists Identify New Treatment Target for Leading Cause of Blindness
[Medical College of Georgia (EurekAlert!)] Medical College of Georgia scientists report that a gene previously implicated in the development of atherosclerotic lesions in coronary arteries could be key to understanding why many people don’t benefit from the most used therapy for neovascular age-related macular degeneration, a leading cause of blindness.
NADPH Oxidase 4-Derived Hydrogen Peroxide Counterbalances Testosterone-Induced Endothelial Dysfunction and Migration
[American Journal of Physiology - Endocrinology and Metabolism] Human mesenteric vascular endothelial cells and human umbilical vein endothelial cells were treated with Testo with or without a NOX4 inhibitor or NOX4 siRNA.
HIF-1α-Dependent Upregulation of Angiogenic Factors by Mechanical Stimulation in Retinal Pigment Epithelial Cells
[Disease Models & Mechanisms] Researchers investigated and characterized the effects of mechanical stimulation on the expression of angiogenic factors in retinal pigment epithelial cells both in vitro and in a mouse model.
Viral Entry and Translation in Brain Endothelia Provoke Influenza-Associated Encephalopathy
[Acta Neuropathologica] Researchers showed that influenza virus entered into the cerebral endothelium and thereby induced influenza-associated encephalopathy. Three-weeks-old young mice were inoculated with influenza A virus.
Specific research topics covered in Endothelial Cell News include the roles of endothelial cells in the regulation of physiological processes, as well as their implications in tumor progression, cardiovascular disease, endometriosis, wound healing, tissue regeneration and other diseases and disorders. We also provide updates on the latest job postings and upcoming events, helping connect everyone within the endothelial cell research field.
