γδ T cells were investigated in a longitudinal cohort of preterm neonates using next-generation sequencing, flow cytometry, and functional assays. During the first year...

Investigators developed and validated a pathomics-driven ensemble model for predicting the response to immune checkpoint inhibitors in gastric cancer, using H&E-stained whole slide images.

Scientists reported a case of fulminant hepatitis in a hepatitis B surface antigen-positive patient with aggressive adult T cell leukemia-lymphoma who received monotherapy with...

Investigators assessed the ability of DONQ52 to inhibit coeliac disease patient-derived T cell responses to the most immunogenic gluten peptides encompassing immunodominant T cell...

Researchers investigated whether and how bevacizumab regulated ferroptosis and immune activity in liver cancer. They performed RNA-sequencing in bevacizumab-treated human liver cancer cell line...

Researchers showed that expression of HLA-DR, high-affinity receptors for Staphylococcal enterotoxins, by keratinocytes correlated with IFN-γ expression in the tumor microenvironment. Importantly, IFN-γ induced...

The authors present how arming Vδ2-T cells might be the basis for next-generation immunotherapies against solid tumors. Following a comprehensive overview of γδ T...

Researchers showed unique dysregulated pathways in splenic compared to bone marrow endothelial cells during atherosclerosis, including perturbations of lipid metabolism and endocytic trafficking pathways.

Investigators showed that FOXC1 was essential for retinal angiogenesis. Endothelial cell-specific loss of Foxc1 impaired retinal vascular growth and expression of Slc3a2 and Slc7a5,...

Scientists reported a Sox17-Erg direct reprogramming approach that used cardiac fibroblasts to create differentiated endothelial cells that demonstrated endothelial-like molecular and physiological functions in...

The obesity-related hypertension rats induced by high-fat diet for 28 weeks and the human umbilical vein endothelial cells-treated by palmitic acid were used to...

Researchers demonstrated that a gp120-based vaccine can elicit antibodies capable of tier 2-HIV neutralization. They reported the isolation and characterization of a CD4-binding site...