[Leukemia] The authors provide a comprehensive review of the various studies and evidence available on Earth and in space assessing the relationship between ionizing radiation and increased risk of leukemia.

[Blood] Scientists showed that the mitochondrial protease ClpP is both a cell-intrinsic metabolic vulnerability and an actionable immunogenic trigger in multiple myeloma.

[Leukemia] Researchers demonstrated that human cultured and primary acute B cell/T cell leukemia and lymphoma cells required the catalytic activity of HDAC10 for their survival.

[Journal of The American Chemical Society] Researchers showed how amylin incorporation in islet matrices through amylin–Col interactions drives type 2 diabetes progression by impacting β-cell viability and insulin secretion.

[Nature Reviews Bioengineering] The authors explore the structure–function relationship of the bone marrow, emphasizing its complex mechanical behaviour, and discuss the bioengineered models that recapitulate the mechanical properties in the healthy and diseased bone marrow niche.

[Trends In Molecular Medicine] Scientists proposed a new, more clinically grounded, fibroproliferative condition classification that is based on the intent and severity of the fibroproliferation.

[Trends In Cell Biology] The authors review epigenetic regulation of MSC and extracellular vesicle therapies, together with current challenges, aiming to deepen the understanding of donor–recipient communication and inspire next-generation approaches to counteract tissue defects and diseases.

[Molecular Therapy - Nucleic Acids] Researchers explored the development of novel polyethyleneimine (PEI)-based polymers functionalized with both cationic guanidinium and hydrophobic aldehyde groups for efficient transfection to human MSCs.

[Diabetologia] To explore the impact of exocrine damage on beta cell fitness, scientists generated a novel zebrafish model allowing exocrine pancreas ablation, using a nifurpirinol–nitroreductase system.

[Genome Biology] Researchers explored the utilization of transposable elements (TE)-derived enhancers in naïve and expanded pluripotent states by integrative analysis of genome-wide Hi-C-defined enhancer interactions, H3K27ac HiChIP profiling, and CRISPR-guided TE proteomics landscape.

[Human Reproduction Update] The authors follow the PRISMA guidelines, survey the current works of literature on totipotent, naive, and formative PSCs, introduce the molecular and biological characteristics of those stem cells, and give advice for future research.

[Biomaterials Research] The authors developed a long-term hiPSC culture platform based on a cross-linked cyclosiloxane polymer matrix that preserves pluripotency with naïve-like characteristics.